Vitamin D3 may increase bacterial richness in the upper gastrointestinal tract and reduce opportunistic pathogens, says a new study from Austria.

Vitamin D3 and the human microbiome

Vitamin D3 may increase bacterial richness in the upper gastrointestinal tract and reduce opportunistic pathogens, says a new study from Austria.

Scientists from the Medical University of Graz report that high daily doses of vitamin D3 for five weeks led to significant reductions in bacteria such as Pseudomonas spp. and Escherichia/Shigella spp.

“The marked reduction in Gammaproteobacteria, which include typical opportunistic pathogens and the increase in phylotype richness, supports the beneficial effect of a high-dose vitamin D3 supplementation on the human gut microbiome,” wrote the researchers.

“This might in part explain the effects of a vitamin D-rich diet on IBD or bacterial infections and encourage studying the effects of vitamin D in these patients.”

Study details

The researchers recruited 16 healthy people to participate in their open-label, pilot study.

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